Use Cases

• Identify sets of drugs with similar transcriptional signatures
• Identifying chemical perturbagens emulating genetic perturbation of MTOR protein
• Mechanism of action analysis via connection to genetic perturbation signatures
• Proteo-genomics analysis of cancer driver events in breast cancer
• Reversing Estrogen Receptor (ER) signature profile
• Reversing MTOR loss-of-function signature profile
• What are my GENES doing in LINCS dataset?